Tesofensine
$225.00
Tesofensine 500mcg x 100 Capsules | Research Peptide for Metabolic and Cognitive Support
Originally investigated for neurological conditions, Tesofensine gained attention in research due to an unexpected secondary effect observed in clinical trials—significant reductions in body weight independent of added exercise or dietary changes.
How It’s Believed to Work
Research suggests Tesofensine may influence several key neurotransmitters:
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Dopamine reuptake inhibition – associated with reduced cravings and improved reward regulation
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Serotonin reuptake inhibition – may support appetite control and reduced feelings of hunger
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Noradrenaline reuptake inhibition – linked to increased metabolic activity and energy expenditure
Research models have shown Tesofensine to produce notable reductions in body weight compared to several currently available anti-obesity agents, with potential for sustained results.
Tesofensine has also been studied for its impact on BDNF (Brain-Derived Neurotrophic Factor)—a growth factor involved in learning, focus, neuroplasticity, and overall cognitive performance.
Additionally, emerging data suggests Tesofensine may have metabolic-supportive properties consistent with mild uncoupling activity.
Why It’s Gaining Attention in Research
Tesofensine is often explored for its potential to support:
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Appetite regulation
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Enhanced metabolic rate
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Cognitive performance
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Mood, focus, and motivation
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Overall body-composition goals in research settings
15 in stock
Description
Product Description 500mcg x 100 Capsules
Tesofensine is a serotonin–noradrenaline–dopamine reuptake inhibitor (SNDRI) originally researched for its potential applications in neurological conditions such as Parkinson’s and Alzheimer’s. During early studies, researchers observed notable reductions in body weight among participants, which shifted scientific interest toward its potential role in appetite regulation and metabolic research.
In research settings, Tesofensine has been shown to increase the activity of three key neurotransmitters—serotonin, norepinephrine, and dopamine. These neurotransmitters play a role in appetite, energy balance, mood, and overall metabolic signaling. Data from a phase 2b clinical study reported an average weight reduction of approximately 25 pounds over six months, with changes attributed primarily to decreased appetite and modest increases in energy expenditure.
Some researchers note that the compound may continue to demonstrate results over extended durations, with reports of no withdrawal symptoms or dependency after ceasing use following long-term administration. While individual responses vary, these observations suggest the compound may be well-tolerated within controlled research environments.
Important Considerations
Some users have reported that Tesofensine may have stimulating effects that can impact sleep patterns. Individuals with a history of SSRI use may be more sensitive to this response. For this reason, many researchers recommend avoiding administration later in the day.
Important Notice
The information provided about this compound is for research and educational purposes only. Tesofensine is not approved by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Legal Disclaimer
• This product is sold strictly as a raw research compound.
• It is not a dietary supplement, pharmaceutical, or medication.
• It is intended only for qualified researchers with the appropriate training and equipment to handle such materials safely.
• By purchasing this product, you agree to indemnify the supplier against any adverse outcomes resulting from improper handling or misuse.
For safety, keep all research materials out of the reach of children. Limited data is available regarding this compound, and improper handling may lead to adverse effects.
All information on this website is for educational purposes only and is not intended as a substitute for professional medical advice. Always consult a licensed healthcare provider regarding any health-related questions. Never disregard or delay seeking medical guidance based on material found on this site.





